Below is a list and references to the ten most important works of research:
Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies.
Germovsek E, Lutsar I, Kipper K, Karlsson MO, Planche T, Chazallon C, Meyer L, Trafojer UMT, Metsvaht T, Fournier I, Sharland M, Heath P, Standing JF; NeoMero Consortium .
J Antimicrob Chemother. 2018 Jul 1;73(7):1908-1916. doi: 10.1093/jac/dky128.
Pharmacokinetics of Penicillin G in Preterm and Term Neonates.
Padari H, Metsvaht T, Germovsek E, Barker CI, Kipper K, Herodes K, Standing JF, Oselin K, Tasa T, Soeorg H, Lutsar I.
Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02238-17. doi: 10.1128/AAC.02238-17.
A highly sensitive method for the simultaneous UHPLC-MS/MS analysis of clonidine, morphine, midazolam and their metabolites in blood plasma using HFIP as the eluent additive.
Veigure R, Aro R, Metsvaht T, Standing JF, Lutsar I, Herodes K, Kipper K; CloSed Consortium.
J Chromatogr B Analyt Technol Biomed Life Sci. 2017 May 1;1052:150-157. doi: 10.1016/j.jchromb.2017.03.007.
Development and Evaluation of a Gentamicin Pharmacokinetic Model That Facilitates Opportunistic Gentamicin Therapeutic Drug Monitoring in Neonates and Infants.
Germovsek E, Kent A, Metsvaht T, Lutsar I, Klein N, Turner MA, Sharland M, Nielsen EI, Heath PT, Standing JF.
Antimicrob Agents Chemother. 2016 Jul 22;60(8):4869-77. doi: 10.1128/AAC.00577-16.
An observational study of blood concentrations and kinetics of methyl- and propyl-parabens in neonates.
Mulla H, Yakkundi S, McElnay J, Lutsar I, Metsvaht T, Varendi H, Nellis G, Nunn A, Duncan J, Pandya H, Turner M.
Pharm Res. 2015 Mar;32(3):1084-93. doi: 10.1007/s11095-014-1520-2.
Population Pharmacokinetics and Dosing of Milrinone After Patent Ductus Arteriosus Ligation in Preterm Infants.
Hallik M, Ilmoja ML, Tasa T, Standing JF, Takkis K, Veigure R, Kipper K, Jalas T, Raidmäe M, Uibo K, Starkopf J, Metsvaht T.
Pediatr Crit Care Med. 2019 Jul;20(7):621-629. doi: 10.1097/PCC.0000000000001879
Dosing of Milrinone in Preterm Neonates to Prevent Postligation Cardiac Syndrome: Simulation Study Suggests Need for Bolus Infusion. Hallik M, Tasa T, Starkopf J, Metsvaht T. Neonatology. 2017;111(1):8-11.
Pharmacokinetics and pharmacodynamics of piperacillin/tazobactam during high volume haemodiafiltration in patients with septic shock.
Tamme K, Oselin K, Kipper K, Tasa T, Metsvaht T, Karjagin J, Herodes K, Kern H, Starkopf J.
Acta Anaesthesiol Scand. 2016 Feb;60(2):230-40. doi: 10.1111/aas.12629.
Pharmacokinetics of doripenem during high volume hemodiafiltration in patients with septic shock.
Tamme K, Oselin K, Kipper K, Low K, Standing JF, Metsvaht T, Karjagin J, Herodes K, Kern H, Starkopf J. J Clin Pharmacol. 2015 Apr;55(4):438-46. doi: 10.1002/jcph.432.
Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants.
Jacqz-Aigrain E, Leroux S, Thomson AH, Allegaert K, Capparelli EV, Biran V, Simon N, Meibohm B, Lo YL, Marques R, Peris JE, Lutsar I, Saito J, Nakamura H, van den Anker JN, Sharland M, Zhao W. J Antimicrob Chemother. 2019 Aug 1;74(8):2128-2138. doi: 10.1093/jac/dkz158.